Plain AC3 seems to have no troubles. EAC3, TrueHD all get disrupted by any other UI activity, even drawing subtitles seems to cause it.

The NanoPC T6 with Android tablet or TV builds generally plays videos OK but I get a lot of audio dropouts. Playing in Kodi, using HDMI and passthrough to a Yamaha AVR. The problem seems to be worse with 4K HEVC than with H.264. It also seems to be worse if subtitles are enabled, or any other Kodi U...